Study on pulmonary function changes in infants with human bocavirus or mycoplasma pneumonia
10.3969/j.issn.1000-3606.2014.09.017
- VernacularTitle:人博卡病毒肺炎和支原体肺炎患儿肺功能变化比较
- Author:
Ying CHEN
;
Fang YING
;
Ling LI
;
Meijuan WANG
;
Yongdong YAN
;
Hong XU
;
Guoying GU
;
Wei JI
- Publication Type:Journal Article
- Keywords:
human bocavirus;
mycoplasma pneumonia;
tidal breathing lfow volume loop;
pulmonary function test;
infant
- From:
Journal of Clinical Pediatrics
2014;(9):867-871
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the pulmonary function change in infants with human bocavirus (HBoV) pneumonia or mycoplasma pneumonia (MP) and its clinical signiifcance. Methods One hundred and forty infants under 3 years old who were admitted due to pulmonary infection were recruited from January, 2013 to October, 2013. Among them, HBoV-DNA was detected in 64 cases, and MP-DNA was detected in 76 cases. Thirty eight normal age-matched infants were selected as controls. The shape of tidal breathing lfow-volume loops (TBFVLs) and change of every index were measured with a Pulmonary Testing System (Jaeger MasterScope). Results The ratio of time to peak tidal expiratory lfow (PTEF) to total expiratory time (TPTEF/TE), the ratio of VPTEF to expiratory volume (VPTEF/VE), tidal expiratory lfow at 25%of the remaining tidal volume (TEF25%) and the ratio of TEF25%to PTEF (25/PF) were signiifcantly decreased in infants with HBoV and MP infection as compared with healthy infants (P<0.05). However, there was no signiifcant difference of the above indices between infants with HBoV and MP infection (P>0.05). The shape of TBFVLs in infants with HBoV and MP pneumonia was changed and characterized by left-shifted PTEF and trough-like concave in descending limb. The PTEF was decreased in infants with pulmonary infection. Conclusions HBoV or MP infection results in impaired pulmonary function with manifestations of obstruction in small airway. The shape of TBFVLs in infants with HBoV and MP pneumonia is characterized by left-shifted PTEF and trough-like concave in descending limb.
