Comparison of internal gross target volumes delineated on the maximum intensity projection of four-dimensional CT images and positron emission tomography-CT for primary thoracic esophageal cancer
10.3760/cma.j.issn.0254-5098.2014.09.010
- VernacularTitle:基于4 D-CT的最大密度投影图像与基于PET-CT不同SUV值勾画的胸段食管癌原发肿瘤IGTV比较研究
- Author:
Yanluan GUO
;
Jianbin LI
;
Wei WANG
;
Jinzhi WANG
;
Fengxiang LI
;
Yili DUAN
;
Dongping SHANG
;
Zheng FU
- Publication Type:Journal Article
- Keywords:
Thoracic esophageal cancer;
18 F-FDG PET-CT;
Four-dimensional computed tomography;
Standardized uptake value;
Internal gross target volume
- From:
Chinese Journal of Radiological Medicine and Protection
2014;(9):683-687
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare volumetric size, conformity index (CI), degree of inclusion (DI) of internal gross target volumes (IGTV) delineated on 4D-CT-MIP and PET-CT images for primary thoracic esophageal cancer. Methods Fifteen patients with thoracic esophageal cancer sequentially underwent enhanced 3D-CT, 4D-CT and PET-CT simulation scans. IGTVMIP was obtained by contouring on 4D-CT maximum intensity projection ( MIP). The PET contours were determined with nine different threshold methods (SUV≥2?0, 2?5, 3?0, 3?5), the percentages of the SUVmax(≥20%, 25%, 30%, 35%, 40%) and manual contours. The differences in size, conformity index (CI), degree of inclusion ( DI) of different volumes were compared. Results The volume ratios ( VRs) of IGTVPET2. 5 to IGTVMIP , IGTVPET20% to IGTVMIP, IGTVPETMAN to IGTVMIP were 0?86, 0?88, 1?06, respectively, which approached closest to 1. The CIs of IGTVPET2?0,IGTVPET2.5,IGTVPET20%,IGTVPETMAN and IGTVMIP which were 0?55, 0?56, 0?56, 0?54,0?55, respectively, were significantly larger than other CIs of IGTVPET and IGTVMIP (Z= -3?408-2?215,P <0?05). There were no statistical significance in the DIs of IGTVMIP and IGTVPET2.5,IGTVMIP and IGTVPET20%, IGTVMIP and IGTVPETMAN(0?77,0?82,0?71,0?67, 0?68,0?82,P>0?05). Conclusions The targets delineated based on SUV threshold setting of≥2?5, 20% of the SUVmax and manual contours on PET images correspond better with the target delineated on maximum intensity projection of 4D-CT images than other SUV thresholding methods.