Risk factors for multidrug-resistant Acinetobacter baumannii infection
10.3969/j.issn.1671-9638.2014.09.005
- VernacularTitle:多重耐药鲍曼不动杆菌医院感染危险因素
- Author:
Xidi CHI
;
Shihua GAO
;
Jialong CHEN
;
Guoyu LI
;
Rongjin LIN
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
multidrug resistance;
drug resistance,microbial;
risk factor;
healthcare-as-sociated infection
- From:
Chinese Journal of Infection Control
2014;(9):534-537
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate risk factors for multidrug-resistant Acinetobacter baumannii (MDRAB)infec-tion,so as to provide reference for making preventive and control measures of MDRAB infection.Methods Clinical data of patients with Acinetobacter baumannii (A.baumannii )infection in a hospital between April 2011 and Sep-tember 2012 were surveyed,distribution and specimen sources of A.baumannii and MDRAB were analyzed,and risk factors of MDRAB were assessed.Results Of 236 isolates of A.baumannii,74 (31.36%)were MDRAB .The isolation rate of MDRAB in intensive care unit and neurosurgery department was up to 60.00%(27/45)and 58.06%(18/31)respectively;MDRAB were mainly isolated from wound (45.45%),respiratory tract (34.27%),and urinary tract (17.65%).Univariate analysis revealed that difference in length of hospital stay,use of serum albumin,fiberbronchoscopy, coma days,tracheotomy,use of ventilator,incisional drainage,urinary catheterization,use of carbapenems,and antimicro-bial days in different groups were statistically different (P <0.05).Multivariate logistic regression analysis revealed that tracheotomy(OR95%CI :1.152-7.187),use of ventilator(OR95%CI :1.263 -7.664)were independent risk factors for MDRAB infection.Conclusion Tracheotomy and use of ventilator play an important role in the producing and sprea-ding of MDRAB ,management on drug-resistant bacteria is important in reducing MDRAB infection.
