Advances in pathogenetic mechanisms of diabetic nephropathy
10.3867/j.issn.1000-3002.2014.05.013
- VernacularTitle:糖尿病肾病发病机制研究进展
- Author:
Zitong LLN
;
Chao ZHANG
;
Xuemei SHEN
- Publication Type:Journal Article
- Keywords:
diabetic nephropathy;
pathogenic mechanism
- From:
Chinese Journal of Pharmacology and Toxicology
2014;(5):765-773
- CountryChina
- Language:Chinese
-
Abstract:
This review is intended to present the latest information on the pathogenesis of diabetic nephropathy based on the studies of recent years,involving potential therapeutic targets of diabetic nephropathy,such as hemodynamic dysfunctions,advanced glycation end-product,lipid metabolism disorders,inflammatory cytokines,and oxidative stress. Further studies are mandatory to investigate the effect of various interventions that modulate the pathogenesis in the treatment of diabetic nephropathy.
