New progress in different doses of continuous blood purification therapy in sepsis
10.3760/cma.j.issn.2095-428X.2014.18.014
- VernacularTitle:对不同剂量连续血液净化治疗脓毒症的新认识
- Author:
Jian JI
;
Suyuan QIAN
- Publication Type:Journal Article
- Keywords:
Continuous blood purification;
High-volume hemofiltration;
Low-volume hemofiltration;
Sepsis;
Severe sepsis;
Pediatric
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(18):1413-1416
- CountryChina
- Language:Chinese
-
Abstract:
Spesis/severe sepsis remains a serious problem in pediatric intensive care unit.The mortality of sepsis/severe sepsis is still very high.The waterfall cascade reaction of cell factors is the main reason leading to the continued deterioration of the condition.Continuous blood purification technology can not only remove inflammatory mediators by adsorption and filtration function,but also improve the immune function,even reduce the mortality rate.But there is a controversial topic on the selection of the appropriate dose.This review not only introduces the effects of high-volume hemofiltration and low-volume hemofiltration from different aspects,but also analyses the influencing factors of different effects.