Influence of cardiopulmonary bypass on neurodevelopmental disorder in congenital heart disease children before and after operation
10.3760/cma.j.issn.2095-428X.2014.18.003
- VernacularTitle:体外循环术对先天性心脏病患儿手术前后神经系统发育障碍的影响
- Author:
Jia LI
- Publication Type:Journal Article
- Keywords:
Congenital heart disease;
Cardiopulmonary bypass;
Child;
Neural development
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(18):1368-1371
- CountryChina
- Language:Chinese
-
Abstract:
With the advances of medical management and surgical techniques during cardiopulmonary bypass,children with congenital heart disease are increasingly surviving to adulthood.Research into their neurodevelopmental outcomes in the past 20 years had revealed sobering realizations about the adverse impact on the quality of life of these surgical survivors.A multitude of factors contribute to the incidence and severity of neurodevelopmental abnormalities and can be separated into preoperative,intraoperative,and postoperative events,in addition to genetic contributions and socioeconomic factors.This article highlight some of current understanding of these protean factors.Understanding should lead to modification of current techniques and management strategies,all with the ultimate goal of improving patients' quality of life.
