Role of Beclin-1 in the autophagic regulation of podocyte
10.3760/cma.j.issn.2095-428X.2014.17.001
- VernacularTitle:Beclin-1在肾小球足细胞自噬调控中的作用
- Author:
Li YU
;
Huiyang WANG
- Publication Type:Journal Article
- Keywords:
Podocyte;
Autophagy;
Beclin-1
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(17):1281-1284
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is the cytoplasm and organelles of eukaryotic cells through degradation of itself,aself digest,a series of biochemical process is a kind of programmed cell death,its main function is to remove and degrade its damaged organelles and redundant biological macromolecules,and use the degradation products provide energy,reconstruction and cellular structure,in the steady state of cell and cell life activities play an important role.In recent years,autophagy in glomerular cells play a role of regulation and control have become the focus in the confrontation podocyte damage,including Beclin-1 autophagy related genes in the role of autophagy regulation has caused wide public concern.This article chooses of Beclin-1 in sertoli cell autophagy related research in the role of regulation are reviewed.
