Research progress of coiled-coil domain-containing in carcinoma
10.3760/cma.j.issn.1673-4203.2014.09.016
- VernacularTitle:CCDC与恶性肿瘤的研究进展
- Author:
Jianhui XU
;
Detao YIN
- Publication Type:Journal Article
- Keywords:
Coiled-coil domain-containing;
Invasion;
Carcinoma;
Neoplasm metastasis;
Molecular targeted therapy
- From:
International Journal of Surgery
2014;41(9):635-638
- CountryChina
- Language:Chinese
-
Abstract:
Coiled-Coil domain-containing has many important biological functions and can control the invasion and metastasis of malignant tumor cells and other biological behavior.The abnormal expression of the coiled-coil domaincontaining protein in nasopharyngeal carcinoma,gastric cancer,prostate cancer,pancreatic cancer,breast cancer,colorectal cancer,has a direct link with the phenotype of tumor cell migration,invasion and metastasis.Abnormal protein expression and inhibition of coiled-coil domain-containing related pathways can significantly affect the tumor invasion and metastasis,for the new targeted cancer medicine used in the treatment provides a theoretical basis.
