Research progress of Li-cadherin in hepatocellular carcinoma
10.3760/cma.j.issn.1673-4203.2014.08.015
- VernacularTitle:LI-cadherin与肝细胞癌关系的研究进展
- Author:
Fei WANG
;
Jianguo LI
- Publication Type:Journal Article
- Keywords:
Li-cadherin;
Liver neoplasms;
Tumorigenesis;
Prognosis;
Neoplasm metastasis
- From:
International Journal of Surgery
2014;41(8):553-556
- CountryChina
- Language:Chinese
-
Abstract:
LI-cadherins are a new member of cadherin superfamily,which transmembrane glycoproteins mediate Ca2 + dependent cell-cell adhesion independent of cytoplasmic interactions.They play an pivotal role during tissue development and are critical for the maintenance of junctional complexes between cells and tissues,LI-cadherin high expression in hepatocellular carcinoma results in the decrease of intercellular adhesion effect,cause hepatocellular carcinoma metastasis.
