Research progress of the roles of Polo-like kinase 1 in cell mitosis
10.3760/cma.j.issn.1006-9801.2014.07.021
- VernacularTitle:Polo样激酶1在细胞有丝分裂期作用的研究进展
- Author:
Wei LI
- Publication Type:Journal Article
- Keywords:
Polo-like kinase 1;
Mitosis;
G2/M checkpoint
- From:
Cancer Research and Clinic
2014;26(7):494-497
- CountryChina
- Language:Chinese
-
Abstract:
Polo-like kinase 1 (Plk1) is a serine/threonine kinase that is widely expressed in eukaryotic cells and a key regulator of the cell mitosis.During different stages of mitosis,the locations of Plk1 in cells are different,and can interaction with different substrates,thus it has many biological functions.This article focuses on the functions of Plk1 in different mitotic stages.
