Clinical observation on body gama-knife for the treatment of obstructive jaundice caused by cholangiocarcinoma

VernacularTitle:体部伽玛刀治疗胆管癌所致梗阻性黄疸的临床观察
Author: Zhenzhong XIAO ; Jing CAO
Publication Type:Journal Article
Keywords: Bile duct neoplasms; Body gama-knife; Jaundice,obstructive; Efficacy
From: Cancer Research and Clinic 2014;26(7):473-475
CountryChina
Language:Chinese
Abstract: Objective To observe the symptoms,short and long term effects of body gama-knife in treatment of obstructive jaundice caused by cholangiocarcinoma.Methods 76 patients with obstructive jaundice caused by cholangiocarcinoma were treated with OUR-QGD body gamma-knife.The single therapeutic dose was 3.0-4.0 Gy,isodose curves was 50.0 ％-65.0 ％,the total treatment time was 10-12 times.The liver function,blood routine and adverse effects were monitored.Results Among 76 patients,the jaundice symptoms of 69 cases were significantly reduced,the TBIL and ALT levels were significantly lower than that before treatment (P ＜ 0.05),the ORR was 88.16 ％ (67/76),DCR was 90.79 ％ (69/76).The median TTP was 8.8 months and the median OS was 13.4 months.Conclusions Body gamma-knife treatment for obstructive jaundice caused by cholangiocarcinoma can significantly improve symptoms of patients,and improve their life quality.This treatment has less adverse effects and satisfaction short-time and long-term effects.