Research progress in relationship between S100A6 and digestive cancer
10.3760/cma.j.issn.1006-9801.2014.07.023
- VernacularTitle:S100A6与消化道肿瘤相关性的研究进展
- Author:
Chunmei LI
- Publication Type:Journal Article
- Keywords:
Digestive system cancer;
S100A6;
Signal transduction
- From:
Cancer Research and Clinic
2014;26(7):500-503
- CountryChina
- Language:Chinese
-
Abstract:
S100A6 is the member of the S100 family of EF-hand calcium-binding proteins,which participates in inflammatory reaction and regulates in cell growth,differentiation,growth inhibition and apoptosis.Recently it has been reported that S100A6 plays a key role in neoplastic transformation,proliferation and invasion of tumor,it may become a potential target in the diagnosis and treatment of tumor.Here is to review the recent advances in the research on this molecule,including its structure,function mechanism,and its relationship with the gastrointestinal cancer and so on.