Clinical application and prospect of suspension array technology
10.3760/cma.j.issn.1009-9158.2014.08.004
- VernacularTitle:液相芯片技术在临床检验中的应用进展
- Author:
Wenhong WANG
;
Yuyun XIONG
;
Zhijun JIAO
- Publication Type:Journal Article
- Keywords:
Microspheres;
Flow cytometry;
Microarray analysis;
High-throughput nucleotide sequencing
- From:
Chinese Journal of Laboratory Medicine
2014;37(8):570-572
- CountryChina
- Language:Chinese
-
Abstract:
Suspension array technology,a bead-based multiplex assay,allows a fast and automatic detection of multi-analytes and batch samples in limited sample volume,and it is great potential clinical application in the determination of autoimmune antibodies,muhitumor markers,the phenotype of Human Leukocyte Antigen and the genes of infectious pathogens.However,currently,there are various limitations which hinder the clinical application of this technology broadly.The globally accepted panel of multi analytes,performance criteria,and quality control programs should be established before we get benefit from this high throughput,sensitivity and repeatability platform,which will help to provide scientific and accurate laboratory data for the clinical diagnosis,treatment and prevention.