Surgical treatment of invasive pulmonary fungal infections in patients with hematologic malignancies
10.3760/cma.j.issn.1001-4497.2014.08.008
- VernacularTitle:血液病合并侵袭性肺部真菌感染的外科治疗
- Author:
Jinfeng GE
;
Xiao MA
;
Shiying ZHENG
;
Dong JIANG
;
Haitao MA
- Publication Type:Journal Article
- Keywords:
Hematology;
Fungal infection;
Pulmonary;
Surgical treatment
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2014;30(8):476-478
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarise the experience of surgical treatment of invasive pulmonary fungal infection in patients with hematologic malignancies.Methods From Jan.2000 to Dec.2012,78 hematologic patients with invasive pulmonary fungal infections,including 49 males and 29 females with average age of 29.6 years,underwent surgical treatment.Preoperatively,all patients with 1 to 3 courses of chemotherapy had received average 4 weeks antifungal treatment.There were 58 cases received conventional open thoracic surgery and 20 cases received VATS including lobectomy,segmentectomy,wedgectomy.Results The procedures were successful,the average operation time w as(125.3 ± 35.7) min and intraoperative blood loss was(253.1 ± 42.8) nl.There were no severe postoperative complications.The main complications were excessive effusion (10.2％) and persistence airleak (7.7％).The hospital days was(7.8 ± 2.5) days,no reoperation and death case in 30 days after operation.The follow-up was from 6 to 24 months,38 cases(48.7％) received prophylaetic antifungal treatment,no ease with fungi spread and recurrence.Conclusion The surgical treatment is safe and useful for the hematologic patients with invasive pulmonary fungal infections,when internal medicine conservative treatment is invalid.
