Risk factor for mortality in neonate with congenital esophageal atresia and simple congenital heart disease
10.3969/j.issn.1000-3606.2014.09.018
- VernacularTitle:先天性食管闭锁合并简单先天性心脏病新生儿预后危险因素分析
- Author:
Feng CHEN
;
Yu ZHANG
;
Luquan LI
- Publication Type:Journal Article
- Keywords:
congenital esophageal atresia;
congenital heart disease;
mortality;
risk factor;
respiratory failure;
heart failure
- From:
Journal of Clinical Pediatrics
2014;(9):872-875
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the risk factors for mortality in neonates with congenital esophageal atresia (CEA) and simple congenital heart disease (CHD) including atrial septal defect (ASD), ventricular septal defect (VSD) and patent ductus arteriosus (PDA). Methods The medical records of neonates with CEA and simple CHD who had surgery in Children’s Hospital of Chongqing Medical University from 1998 to 2013, were analyzed retrospectively. Factors including neonatal demographics, laboratory results and complications after surgery were compared between survivor and non-survivor groups. Results Seventy ifve cases were included in this study and the mortality was 10.67%(8/75). There was no signiifcant difference between non-survivor group (n=8) and survivor group (n=67) in factors such as gestational age, birth weight, age of admission, age at surgery, duration of surgery, full blood examination, serum electrolytes, blood gases, prevalence of septicemia, pneumothorax, and cold lesion syndrome. However, the prevalence of respiratory failure and heart failure in non-survivor group was higher than that in survivor group (75%vs. 9%, P=0.000;50%vs. 1.5%, P=0.000, respectively). Conclusions The poor outcome among neonates with CEA plus simple CHD might be associated with respiratory failure and heart failure.
