Application advances in optical imaging of inorganic fluorescent nano-materials-quantum dots
10.3760/cma.j.issn.2095-2848.2014.03.025
- VernacularTitle:无机纳米晶体量子点光学成像应用进展
- Author:
Chongjiao LI
;
Xiaoli LAN
;
Yongxue ZHANG
- Publication Type:Journal Article
- Keywords:
Quantum dots;
Nanotechnology;
Optical imaging;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2014;34(3):246-249
- CountryChina
- Language:Chinese
-
Abstract:
Optical imaging is one of the molecular imaging modalities,and it consists of three imaging methods (fluorescence,bioluminescence and diffusion imaging).For fluorescence imaging,quantum dots (QDs) are inorganic semiconductor nanocrystals with a diameter from 2 to 100 nm.Compared with organic fluorescent dye,QDs have several unique optical properties,such as wide and continuous excitation spectra,narrow and symmetrical emission spectrum,strong fluorescence intensity and high resistance to photobleaching.This article reviews the optical properties of QDs and their development in the field of molecular imaging from in vitro and in vivo applications,as well as the limitations and problems.