ATP stress 99Tcm-MIBI gated myocardial perfusion imaging in diagnosis of in-stent restenosis
10.3760/cma.j.issn.2095-2848.2014.03.003
- VernacularTitle:ATP负荷99Tcm-MIBI门控心肌灌注显像在评价冠状动脉支架植入术后再狭窄中的应用价值
- Author:
Pengfei ZHANG
;
Haishan ZHANG
;
Song CHEN
;
Yingxian SUN
;
Yaming LI
;
Lijuan WANG
- Publication Type:Journal Article
- Keywords:
Coronary diseases;
Stents;
Coronary restenosis;
Adenosine triphosphate;
Tomography,emission-computed,single-photon;
MIBI
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2014;34(3):170-174
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of ATP stress 99Tcm-MIBI G-MPI in evaluating instent restenosis.Methods Seventy-one patients (56 males,15 females,age range:37-83 (60.2±9.5) yeas) who had undergone coronary stent implantation at least 3 months ago,accompanying a typical angina pectoris symptom,were included in this perspective study.All patients underwent ATP stress 99Tcm-MIBI G-MPI and CAG (gold standard) within 1 month.The diagnostic efficiency of ATP stress 99Tcm-MIBI G-MPI on in-stent restenosis was evaluated.Fisher exact probability method was used to analyze data with SPSS 17.0.Results Five patients were excluded because of new stenosis.According to the results of CAG,39 patients with 45 coronary arteries showed in-stent restenosis among 66 patients with 99 coronary arteries.There were 19 patients with myocardial infarction among the 39 patients with in-stent restenosis.Contrarily,there were 16 patients with myocardial infarction among the 27 patients without in-stent restenosis.The diagnostic Se,Sp,Ac,PPV and NPV of ATP stress 99Tcm-MIBI G-MPI for in-stent restenosis were 85％(33/ 39),89％(24/27),86％ (57/66),92％ (33/36) and 80％ (24/30),respectively in 66 patients.Those were 79％(15/19),88％(14/16),83％(29/35),88％(15/17) and 78％(14/18) in patients with myocardial infarction,and 90％ (18/20),91％ (10/11),90％ (28/31),95％ (18/19) and 83％ (10/12) in patients without myocardial infarction (all P＞0.05).Conclusion ATP stress 99Tcm-MIBI G-MPI has high diagnostic efficiency in evaluating in-stent restenosis.
