The role of procalcitonin in patients with different severity grades of acute cholangitis

VernacularTitle:血清降钙素原浓度在急性胆管炎严重程度分级中的作用
Author: Yunxiao LYU ; Jiang HE ; Bin WANG ; Yueming XU ; Weibing DU ; Yunxiao CHENG
Publication Type:Journal Article
Keywords: Procalcitonin; Acute cholanglitis; Severity gradation
From: Chinese Journal of Hepatobiliary Surgery 2014;20(6):428-430
CountryChina
Language:Chinese
Abstract: Objective To evaluate the role of procalcitonin in patients with different severity grades of acute cholangitis (AC).Methods A retrospective study was carried out on 147 patients with different severity grades of AC who were treated from May 2012 to November 2013 at the Dongyang People's Hospital.Results Of 147 patients,the PCT concentrations were (165.63 ± 32.67) pg/ml,(348.97 ± 45.78) pg/ml,(758.91 ± 28.94) pg/ml for patients with mild,moderate and severe AC respectively.The PCT concentrations were significantly higher in patients with severe AC than those with moderate AC (P ＜ 0.05),and also in patients with moderate AC than those with mild AC (P ＜ 0.05).The top three bacteria obtained from blood culture from the different severity grades of AC showed no significant diferences (P ＞ 0.05).Conclusion Serum PCT concentrations were elevated in patients with AC and it may be used as a parameter to assess the severity of AC.