Clinical study of carotid elasticity in subjects with different plasma glucose level by wave intensity

VernacularTitle:瞬时波强技术对不同血糖水平者颈动脉弹性的临床研究
Author: Yuhua ZHANG ; Quanjiang WANG ; Ru LI ; Jianli WEI ; Yanhe SUN
Publication Type:Journal Article
Keywords: Ultrasonography; Prediabetic state; Carotid arteries; Elasticity; Wave intensity
From: Chinese Journal of Ultrasonography 2014;23(5):404-407
CountryChina
Language:Chinese
Abstract: Objective To assess the carotid elasticity using wave intensity(WI) in subjects with different plasma glucose level.Methods 107 subjects were enrolled in this study,according to their plasma glucose levels,subjects were categorized as normal plasma glucose group (group A),normal plasma glucose in higher level group (group B) and pre-diabetes group (group C).Carotid WI examination was performed and analyzed.The parameters included magnitude of the peak during late systole (W2),negative area during the mid-ejection (NA),and stiffness parameter (β),pressure strain elasticity modulus (Ep),arterial compliance(AC),augmentation index(AI),one point pulse wave velocity(PWVβ).Results Compared to group A,W2,β,Ep,PWVβ increased significantly while AC decreased in group C(P ＜0.05),but there was no obvious difference of NA between two groups.Furthermore,this statistically difference was not found in group B(P ＞0.05).Conclusions Carotid elasticity have been altered in pre-diabetes group which can be evaluated by WI,but no marked change is observed in normal plasma glucose of higher level group.