The clinical value of inflammation-related factors in prediction of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage
10.3760/cma.j.issn.1008-1372.2014.05.008
- VernacularTitle:炎症相关指标在预测动脉瘤性蛛网膜下腔出血后迟发性脑缺血的临床价值
- Author:
Longjin SHA
;
Guozhong ZHANG
;
Wenfeng FENG
;
Songtao QI
- Publication Type:Journal Article
- Keywords:
Subarachnoid hemorrhage/complications;
Brain ischemia/etiology;
Leukocyte count;
Blood sedimentation;
C-reactive protein
- From:
Journal of Chinese Physician
2014;16(5):605-607
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of inflammation-related factors [white blood cell count,erythrocyte sedimentation rate (ESR),and C-reactive protein] in predicting delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.Methods The aneurysmal subarachnoid hemorrhage in 217 cases according to whether the occurrence of delayed cerebral ischemia were divided into 2 groups:delayed cerebral ischemia (DCI) group (n =69) and non DCI group (n =148).A retrospective analysis of 217 cases of patients was performed with inflammation-related factors,and its relationship with clinical prognosis of patients with DCI was also analyzed.Results The inflammation-related factors (WBC count,erythrocyte sedimentation rate,and C-reactive protein) in DCI group were significantly higher than those in non DCI group with a statistically significant difference (P ＜ 0.05).The follow-up results showed that there were 33 patients died,12 cases of plant survival,and 12 patients with severe disability in DCI group,which had a statistically significant difference relative to non DCI group (P ＜ 0.05).Spearman analysis showed that there was a significantly negative relationship between inflammation-related factors (white blood cell count,ESR,C-reactive protein) and glasgow prognostic score (GOS) in DCI group(r =-0.877,-0.683,-0.841,P ＜0.05).Conclusions The inflammation-related factors can be used as one of method to predict delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.
