Clinical analysis of arterial perfusion intervention combined with radiation and chemotherapy in the treatment of locally advanced cervical cancer
10.3760/cma.j.issn.1673-4904.2014.15.016
- VernacularTitle:动脉灌注介入联合放化疗治疗局部晚期宫颈癌的临床分析
- Author:
Dongmei ZHANG
- Publication Type:Journal Article
- Keywords:
Uterine cervical neoplasms;
Arterial perfusion intervention
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(15):46-48
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effect of artery perfusion intervention combined with radiation and chemotherapy in the treatment of locally advanced cervical cancer,and to provide clinical reference.Methods One hundred and eighteen cases with locally advanced cervical cancer patients were divided into observation group and control group by random digits table method,each group 59 cases,all patients in two groups received preoperative chemoradiation,observation group based on this,and added arterial perfusion interventional chemotherapy,compared the clinical curative effect of two groups.Results The effective rate in observation group was significantly higher than that in control group[93.22％(55/59) vs.77.97％(46/59)] (x2 =5.567,P=0.018).Seventeen cases in observation group with Ⅰ and Ⅱ degree of nausea,vomiting,2 cases with Ⅲ degree of nausea,vomiting,4 cases with Ⅰ degree of bone marrow suppression,the incidence of adverse reactions were 38.98％(23/59);18 cases in control group with Ⅰ and Ⅱ degree of nausea,vomiting,3 cases with bone marrow suppression,the incidence of adverse reactions were 35.59％ (21/59),there was no statistically significant difference between two groups (x2 =0.145,P =0.703).Conclusions Preoperative arterial perfusion intervention combined with chemoradiotherapy can effectively improve the curative effect for locally advanced cervical cancer,and has no increase in adverse reactions,and has important clinical value.
