Clinical effect of diazepam and phenobarbital in children with febrile convulsion

VernacularTitle:地西泮联合苯巴比妥对小儿惊厥患者的临床效果研究
Author: Wenli PEI
Publication Type:Journal Article
Keywords: Diazepam; Phenobarbital; Seizures
From: Chinese Journal of Postgraduates of Medicine 2014;37(15):41-42
CountryChina
Language:Chinese
Abstract: Objective To study the clinical effect of diazepam and phenobarbital in children with febrile convulsion.Methods Seventy cases of febrile convulsion patients were divided into control group (phenobarbital treatment,35 cases) and experiment group (diazepam combined with phenobarbital,35 cases) by random digits table method,and compared the efficacy and complications.Results Two groups were cured within 1 h.The effective rate within 30 min in experiment group was significantly higher than that in control group [88.6％ (31/35) vs.74.3％ (26/35)] (P ＜ 0.05).The recurrent rate in experiment group was significantly lower than that in control group [2.9％ (1/35) vs.14.3％ (5/35)] (P ＜ 0.05).The complications had no statistically significant differences between two groups(P ＞ 0.05).Conclusions Diazepam combined with phenobarbital are very effective for children with febrile convulsion,can greatly improve clinical efficacy,decrease recurrent rate,and won't produce adverse reaction and complications,are the ideal treatment in the clinical treatment.