Effect of miRNA on radiosensitivity and chemosensitivity in glioma stem cells
10.3760/cma.j.issn.1673-422X.2014.06.002
- VernacularTitle:微小RNA与胶质瘤干细胞放化疗敏感性
- Author:
Jiarong CHEN
;
Quanquan SUN
;
Tian ZHANG
;
Yanmeng LU
;
Yawei YUAN
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Glioma;
Neoplastic stem cells;
Radiotherapy;
Drug therapy
- From:
Journal of International Oncology
2014;41(6):405-407
- CountryChina
- Language:Chinese
-
Abstract:
The expression of microRNA (miRNA) is closely related to radio-chemosensitivity in glioma stem cells (GSCs).Moreover,the growth of glioma stem cells could be inhibited comprehensively by increasing radio-chemosensitivity and apoptosis,simultaneously with the regulation of a single miRNA,which has been confirmed by some researches.Thereby microRNA is prospective for the adoption as a specific agent in targeted therapy of glioma,so as to increase the radio-chemosensitivity in glioma stem cells.
