Correlation between hyperglycemia and early death in patients with intracerebral hemorrhage after microinvasive evacuation of hematoma
10.3760/cma.j.issn.1673-4165.2014.06.003
- VernacularTitle:高血糖与脑出血患者微创血肿清除术后早期死亡的相关性
- Author:
Bin ZHANG
;
Fang XU
;
Wei CHEN
;
Wei LI
- Publication Type:Journal Article
- Keywords:
Cerebral Hemorrhage;
Hyperglycemia;
Blood Glucose;
Hematoma;
Drainage;
Suction;
Surgical Procedures,Minimally Invasive;
Treatment Outcome;
Risk Factors
- From:
International Journal of Cerebrovascular Diseases
2014;22(6):411-415
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of hyperglycemia on the risk of early death after microinvasive evacuation of hematoma in patients with spontaneous intracerebral hemorrhage (SICH).Methods Patients with SICH received microinvasive evacuation of hematoma were analyzed retrospectively.The laboratory results including medical history,baseline clinical information,imaging examination,and blood glucose of the patients were collected.The patients were divided into either a death group or a survival group according to whether they died or not at day 30 after procedure.Multivariatelogistic regression analysis was used to determine the independence risk factors for early death after procedure,Results A total 321 patients with SICH received microinvasive evacuation of hematoma were enrolled during the study,63 in the death group and 258 in the survival group.The proportions of age (63.18 ± 11.93 years vs.59.05 ± 12.73 years; t=2.341,P=0.019),baseline hematoma volume (median [M],interquartile range [IQR]:(67 [42-75] ml vs.40 [34-65] ml; U=4.681,P＜0.001),National Institutes of Health Stroke Scale (NIHSS) score (M,IQR:26 [9-36] vs.17 [7-24]; U=2.508,P=0.012),and baseline hyperglycemia(46.0％ vs.26.4％ ;x2 =9.296,P =0.002) of the death group were significantly higher than those of the survival group.Multivariate logistic regression analysis showed that age ≥65 years (odds ratio [OR]2.594,95％ confidence interval [CI] 1.118-3.768; P=0.034),baseline hyperglycemia (OR 3.813,95％ CI2.093-10.867; P=0.027),baseline hematoma volume ≥80 ml (OR 19.773,95％ CI 8.352-31.624; P＜0.001),and NIHSS score ≥15 (OR 9.145,95％ CI 4.195-15.733; P=0.019) were the independent risk factors for early death after microinvasive evacuation of hematoma in patients with SICH.Conclusions Hyperglycemia on admission may be an independent risk factor for early death after microinvasive evacuation of hematoma in patients with SICH.
