Biological characterizations of street strain of rabies virus in Fujian Province,China
10.3969/cjz.j.issn.1002-2694.2014.07.005
- VernacularTitle:福建省狂犬病毒街毒株分离鉴定及生物学特性研究
- Author:
Jianming ZHANG
;
Yanqin DENG
;
Linglan WANG
;
Daihua LIN
;
Xiuhui YANG
;
Yansheng YAN
- Publication Type:Journal Article
- Keywords:
rabies virus;
street strain;
isolation and identification;
biological characteristics
- From:
Chinese Journal of Zoonoses
2014;(7):684-687
- CountryChina
- Language:Chinese
-
Abstract:
In this study ,street trains were isolated from brain of suspected rabid dogs via mouse inoculation technique (MIT) and cell culture inoculation technique (CIT) .Virus was identified by FAT ,RT-PCR and sequencing .Then ,the virus’ biological characteristics were analysed .The TCID50 test results demonstrated that viral titers were not high ,which showed the BHK-21 cells was not the best host cell of rabies viral strain .The LD50 test results showed it was a strong strain of rabies virus .These results laid a strong foundation for rabies laboratory research in Fujian .