Relationship Between the Progression Rate of Corotid Maximal Plaque Area and the Risk of New Ischemic Cardiovascular Disease
10.3969/j.issn.1000-3614.2014.07.014
- VernacularTitle:颈动脉最大斑块面积的进展速率与新发缺血性心血管事件的关系
- Author:
Meng WANG
;
Gaoqiang XIE
;
Hao WANG
;
Fuxiu REN
;
Lirong LIANG
;
Liancheng ZHAO
;
Ying YANG
;
Wuxiang XIE
;
Ping SHI
;
Yangfeng WU
- Publication Type:Journal Article
- Keywords:
Carotid plaque;
Ischemic cardiovascular disease;
Ultrasonography
- From:
Chinese Circulation Journal
2014;(7):532-536
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the progression rate of cortid maximal plaque area and the risk of new ischemic cardiovascular disease (ICVD) in a rural cohort in Beijing.
Methods: The PRC-USA collaborative study had been regularly conducted in Shijingshan area in Beijing. The carotid ultrasound examination, ICVD risk factor and acute cardiovascular events follow-up were conducted in those participants. A total of 1479 subjects who received at least 2 carotid ultrasound examinations and had no cardiovascular disease before the second ultrasound were studied. They were divided into 5 groups:①Control group, the participants had no plaque detected by 2 ultrasounds; ② New plaque group, new plaque was found at the second ultrasound examination; ③ Plaque regression group; ④ Plaque stabilized group and ⑤ Plaque progression group. The hazard ratio (HR) between the progression rate of corotid maximal plaque area and new ICVD events was estimated by Cox proportional hazard regression analysis .
Results: Compared with Control group, the HR for new ICVD events were higher in groups②,③,④and⑤at 3.5, 5.7, 6.2 and 7.3 respectively, all P<0.05. The increasing trend of HRs remained signiifcant with the adjusted age and gender, P<0.001.
Conclusion: The progression rate of maximal corot id plaque area rate could predict the risk of new ICVD events in clinical practice.
