Application of multiphoton microscopy diagnosis of early phase tumors of digestive system
- VernacularTitle:多光子显微镜诊断早期消化系统肿瘤的研究进展
- Author:
Limei MA
;
Yin ZHANG
;
Zhining FAN
- Publication Type:Journal Article
- Keywords:
Multiphoton microscopy;
Tumors of digestive system;
Real-time diagnosis;
Histopathology
- From:
Journal of Medical Postgraduates
2014;(7):743-745
- CountryChina
- Language:Chinese
-
Abstract:
The morbidity and mortality of tumors of digestive system is much higher in recent years .Realizing diagnosis of early phase tumors can improve the surgical resection rate and prolong survival time of patients .Compared with traditional diagnosis methods, multiphoton microscopy has got an obvious improvement in the penetration depth .Furthermore, phototoxicity and photo-bleaching has been largely reduced .Combining with the second harmonic microscopy , the change of collagen fibers can be observed in the organization.MPM can achieve early diagnosis of cancer at the cellular level .Therefore, multiphoton microscopy , with the imaging characteristics of unique high resolution , real-time, nondestructive , deeply spectral resolution , is of great potential in the diagnosis of early stage tumors of digestive system .Based on the latest research results , this review summarizes the latest progress of multiphoton microscopy diagnosing early phase of gastrointestinal tumor .
