Research progress in the correlation between microRNAs and glioma
- VernacularTitle:MicroRNA 与神经胶质瘤关系的研究进展
- Author:
Caiyun WU
;
Chunni ZHANG
- Publication Type:Journal Article
- Keywords:
MicroRNA;
Glioblastoma;
Molecular markers;
Target genes
- From:
Journal of Medical Postgraduates
2014;(7):746-750
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs ( miRNAs) are a kinds of small non-coding RNA that regulate the expression of gene at the posttran-scriptional level and play important roles in a variety of physiological and pathological processes such as proliferation , differentiation and apoptosis.Recently, it has been reported that miRNAs expression abnormalities are closely associated with the initiation and devel -opment of glioma .Moreover , the expression levels of some miRNA are specifically involved in the molecular pathogenesis of glioma , revealing their great potential as a class of novel biomarkers for cancers and therapeutic targets .In this review , we summarizes the lat-est researches on miRNA and glioma .
