Efficacy and Safety Comparison Between Sevoflurane Inhalation Combining Laryngeal Mask Airway and Ketamine Anesthesia for Anesthesia Induction
10.3969/j.issn.1000-3614.2014.07.015
- VernacularTitle:比较七氟烷吸入复合应用喉罩与氯胺酮基础麻醉在麻醉诱导中的有效性和安全性
- Author:
Pengsheng TIAN
;
Quanyi ZHANG
;
Chaobin ZHANG
;
Jie DING
;
Fuxia YAN
;
Lihuan LI
- Publication Type:Journal Article
- Keywords:
Ketamine;
Sevolfurane;
Laryngeal mask airway;
Pediatric cardiac surgery;
Induction
- From:
Chinese Circulation Journal
2014;(7):537-539
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Compared with ketamine anesthesia, to investigate sevoflurane inhalation combining laryngeal mask airway for anesthesia induction in pediatric cardiac surgery.
Methods:A total of 40 pediatric patients with congenital heart diseases received elective cardiac surgery in our hospital from 2013-08 to 2014-01 were studied. The children were from 6 months to 2 years of age and randomly divided into 2 groups, n=20 in each group. Sevolfurane group, the children inhaled the mixture of 8%sevolfurane and 100%O2, laryngeal mask airway was used upon losing consciousness for mechanical ventilation, the anesthesia was maintained by (3-4)% sevolfurane inhalation to facilitate central venous catheter placement. Ketamine group, the children received intramuscular injection of ketamine (7 mg/kg)+atropine (0.01 mg/kg). The peripheral venous line was established upon losing consciousness, the intravenous midazolam (0.1 mg/kg), pipecuronium (0.10 mg/kg), fentanyl (5 μg/kg) were applied, then tracheal intubation was performed for mechanical ventilation and the anesthesia was maintained by (0.5-1)%sevolfurane to facilitate central venous catheter placement.
Results: Sevoflurane group had the shorter time for losing the consciousness than that in Ketamine group (48.90 ± 3.93) s vs (577.85 ± 116.41) s, P<0.05 and the shorter time for ifnishing the central venous catheter placement (11.15 ± 2.48) min vs (24.15 ± 4.02) min, P<0.05. The average blood pressure and heart rate were similar between 2 groups after laryngeal mask or tracheal intubation, P>0.05. The arterial PH value, PaCO2, BE and lactatein were similar between 2 groups, P>0.05.
Conclusion: Sevoflurane inhalation combining laryngeal mask airway could shortening anesthesia preparation time with simple management. It provided an important anesthesia option in pediatric cardiac surgery.
