Effect of tea polyphenols intake on ethanol-induced liver injury

VernacularTitle:茶多酚对酒精性肝损伤过氧化的影响
Author: Yuanting TANG ; Xiaoqin GUAN ; Yongmei JIANG ; Xinai YUE ; Ping CHEN ; Ying PENG ; Jie YU
Publication Type:Journal Article
Keywords: tea polyphenols; ethanol-induced liver injury; ROS
From: Chongqing Medicine 2014;(21):2736-2738
CountryChina
Language:Chinese
Abstract: Objective To establish the cell model of ethanol-induced liver injury and explore the protective effects of tea poly-phenols (TP)on ethanol-induced liver injury .Methods Cell morphology were observed by microscope ,and then alanine aminotrans-ferase (ALT) ,nmda transaminase (AST) ,gamma GGTP ,GGT and ROS changes were detected .Results Alcohol maked L02 hepa-tocyte fatty degeneration .Compared with ethanol group ,steatosis in TP + ethanol group was lighter ,its ALT ,AST ,GGT content and intracellular ROS reduced .Conclusion TP can decrease cell fatty change degree in vitro experiments ,improue the enzymology indexes ,reduce the generation of reactive oxygen species to avoid liver damage .