Change of the hilar periportal space in the patients with chronic hepatitis B and liver cirrhosis after hepatitis B
10.3969/j.issn.1671-8348.2014.21.010
- VernacularTitle:慢性乙型肝炎及乙型肝炎后肝硬化门脉前间隙的变化
- Author:
Jian SHU
;
Jiannong ZHAO
;
Fugang HAN
;
Guangcai TANG
;
Xinwen HUANG
- Publication Type:Journal Article
- Keywords:
hepatitis B,chronic;
liver cirrhosis;
hilar periportal space;
magnetic resonance imaging
- From:
Chongqing Medicine
2014;(21):2716-2719
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate thickness of the hilar periportal space and caudate-right lobe ratio in the patients with chro-nic hepatitis B and liver cirrhosis after hepatitis B .Methods Eighty-four patients who were clinically and histologically diagnosed with chronic hepatitis B or cirrhosis and 18 healthy subjects without history of liver disease underwent abdominal MRI .The rela-tionship among liver fibrosis degree ,hilar periportal space and caudate-right lobe ratio were observed .Results There was signifi-cant correlation between the hilar periportal space and hepatic fibrosis for chronic hepatitis and cirrhosis (rs = 0 .546 ,P< 0 .01) . There was significant difference between S2 and S3 for thicknesses of the hilar periportal space(P<0 .01) ,and no significant differ-ence among S3 ,S4 and cirrhosis(P=0 .188) .A cutoff value of 9 mm for the hilar periportal space had a sensitivity of 85 .37% and a specificity of 76 .79% for a diagnosis of hepatic fibrosis with S3 or higher .There was no significant correlation between the caudate-right lobe ratio and hepatic fibrosis(rs = -0 .155 ,P=0 .119) .Conclusion Thicknesses of the hilar periportal space increase gradu-ally with hepatic fibrosis in patients with chronic hepatitis B and cirrhosis ,with a high sensitivity and specificity for a diagnosis of hepatic fibrosis with S3 or higher .
