Comparison of diagnosis values of combined detection of IAM,hs-CRP,MYO,CK-MB,hs-cTnT in acute coronary syndrome
10.3969/j.issn.1673-4130.2014.14.019
- VernacularTitle:IMA、hs-CRP、MYO、CK-MB、hs-cTnT 联合检测在急性冠脉综合症诊断中的价值比较
- Author:
Qingfang GUO
;
Xingxin LI
;
Xiaofei LAI
- Publication Type:Journal Article
- Keywords:
ischemia modified protein;
hypersensitive C reactive protein;
myoglobin;
creatine kinase MB;
ultra-sensitive troponin T;
acute coronary syndrome
- From:
International Journal of Laboratory Medicine
2014;(14):1861-1863
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of serum ischemia-modified protein (IMA),hypersensitivity C reaction protein (hs-CRP),myoglobin (MYO)creatine kinase MB (CK-MB)and ultra-sensitivity troponin T (hs-cTnT)in the early diagnosis of patients with acute coronary syndrome(ACS).Methods Serum levels of IMA,hs-CRP,MYO,CK-MB and hs-cTnT were meaused in 94 patients with ACS[including 40 cases of unstable angina pectoris(UAP),20 cases of non-ST segment elevation myocardial in-farction(NSTEMI),non-Q wave myocardial infarction and 34 cases of ST segment elevation myocardial infarction(STEMI),Q wave myocardial infarction]and 99 cases of controls.The efficiency,sensitivity,specificity,negative and positive predictive values in the early diagnosis of ACS were compared among 5 kinds markers by the ROC curve.Results The detection results of serum IMA,hs-CRP,MYO,CK-MB and hs-cTnT had statistically significant differences between the UAP,NSTEMI and STEMI groups with the normal control group (P <0.05),serum IMA,hs-CRP,MYO,CK-MB and hs-cTnT had statistically significant differences between the UAP group with the NSTEMI group and between the UAP group with STEMI group (P <0.05),but the difference between NSTEMI and STEMI group group was not statistically significant (P >0.05).Conclusion In the patients with ACS,the multiple indicators combined detection can achieve the early diagnostic value.
