Detection of serum hyper sensitive C-reactive protein level in patients with acute ischemic stroke and its clinical significances
10.3969/j.issn.1673-4130.2014.14.020
- VernacularTitle:急性缺血性脑卒中患者血清 hs-CRP 的检测及其临床意义
- Author:
Fenghua ZHANG
;
Hong ZHU
;
Kuo XU
;
Yan JIN
;
Yanan GU
;
Bing LI
- Publication Type:Journal Article
- Keywords:
ischemic stroke;
Hypersensitive C-reactive protein;
clinical significanles
- From:
International Journal of Laboratory Medicine
2014;(14):1864-1865
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the level of hypersensitive C-reactive protein (hs-CRP)in the patients with acute ischemic stroke(AIS)and its clinical significance.Methods The BNⅡhighly sensitive automatical scattering turbidimetric immunity analy-zer was adopted to detect serum hs-CRP level in 64 cases of AIS and contemporaneous 32 individuals with healthy physical examina-tion as the control group.The data of AIS cases were retrospectively analyzed.Results The positive rate of hs-CRP was 53.3% in the AIS group and 9% in the control group with statistically significant difference between them(P <0.05);the overall levels of hs-CRP in the AIS group was in inconformity to the normal distribution,the median was 4.26mg/L,which in the control group was (0.99 ± 0.72 )mg/L,there was statistically significant difference between them (P < 0.05 );the average level of hs-CRP was (5.03±1.51)mg/L in the AIS male group and (2.79 ± 1.09)mg/L in the AIS female group,the difference between them had sta-tostical significance(P <0.05).Conclusion The serum hs-CRP level in the AIS patients is higher than that in the healthy crowd with statistical difference(P <0.05).The age and sex may be the causes influencing serum level of hs-CRP in the AIS patients.The average age in the AIS patients with positive hs-CRP is higher than that with negative hs-CRP.Middle-aged and elderly people with hypertension and diabetes are much more dangerous than healthy people in getting AIS.
