Change of microinflammatory indicators in maintenance hemodialysis patients

VernacularTitle:维持性血液透析患者体内微炎症指标变化的探讨
Author: Ling ZHANG ; Shugen XU ; Houzhao WANG
Publication Type:Journal Article
Keywords: maintenance hemodialysis; microinflammation; high sensitivity C-reactive protein
From: International Journal of Laboratory Medicine 2014;(14):1842-1843
CountryChina
Language:Chinese
Abstract: Objective To investigate the changes of microinflammatory indicators in the maintenance hemodialysis patients to provide the new idea for clinical treatment.Methods Serum super sensitive C reactive protein (hs-CRP),interleukin 6(IL-6),tumor necrosis factorα(TNF-α),homocysteine(Hcy),malondialdehyde(MDA),albumin(ALB),hemoglobin,transferrin(Tf)levels and in-tact parathyroid hormone(iPTH)levels in 80 patients with hemodialysis were detected and the results were compared with those in the normal healthy population.Results The hs-CRP,IL-6,TNF-αlevels in the maintenance hemodialysis patients were significantly higher than those in the normal healthy population (P <0.05 ),the CRP level was positively correlated with IL-6,TNF-α,Hcy, MDA and iPTH levels and negatively correlated with ALB and Tf levels.Conclusion The microinflammatory indicators in the ma-intenance hemodialysis patients are higher than those in the normal people,which urgently need to conduct the related treatment.