Analysis of women′s genital human papillomavirus infection and genotype distribution in Shenzhen
10.3969/j.issn.1673-4130.2014.14.026
- VernacularTitle:深圳地区女性生殖道 HPV 感染及基因型结果分析
- Author:
Guangxing MAI
;
Zehao YAN
;
Likuan XIONG
;
Kelin XIAO
;
Mingyue LUO
;
Yong XIA
- Publication Type:Journal Article
- Keywords:
HPV;
genotype;
PCR;
reverse dot blot hybridization
- From:
International Journal of Laboratory Medicine
2014;(14):1878-1879
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the female human papillomavirus(HPV)infection situation in Baoan district,the HPV pos-itive rates in different age groups and the subtypes distribution.Methods PCR followed with reverse dot blot was performed to ex-amine 23 kinds of HPV genotypes in 2 627 female patients in our hospital from the January 2011 to December 2012.Results In 2 627 samples,the positive rate of HPV was 23.94% (629 cases),in which the infection rate of single low-risk type was 15.1%(95 cases),the main HPV genotype was HPV43 (7.79%);the infection rate of high-risk type was 55.17% (347 cases),the 3 most prevalent HPV genotypes were HPV52 (12.56%),HPV16 (9.86%)and HPV58 (7.79%).The multiple HPV infection ac-counted for 29.73% (187 cases).The HPV infection rates in different age groups were 50.0% in age 15-20 years,24.7% in age 21-30 years,20.8% in age 31-40 years,25.8% in age 41 -50 years,42.1% in age >50 years respectively,the differences had statistical significance.Conclusion The HPV infection rate is 23.94% in Bao′an district.The most prevalent HPV genotypes are HPV 52,16,58,43.Women in age 15-20 years old have a higher infection rate.
