Different chemotherapy regimens comparing the efficacy and safety in elderly patients with advanced gastric cancer
10.3969/j.issn.1006-5725.2014.13.022
- VernacularTitle:不同化疗方案治疗老年晚期胃癌患者的疗效和安全性比较
- Author:
Jihua ZHENG
;
Juan ZHOU
;
Bo XIE
;
Zhiyong XU
;
Yingjuan WEN
;
Jinrong LIN
;
Weimin ZHANG
- Publication Type:Journal Article
- Keywords:
Advanced gastric cancer;
Chemotherapy;
Elderly patients;
Comparison
- From:
The Journal of Practical Medicine
2014;(13):2086-2087
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze and compare efficacy and safety of different chemotherapy regimens in the treatment of elderly patients with advanced gastric cancer. Methods 60 elderly patients admitted to our hospital with advanced gastric cancer were selected as research subjects , and divided into experimental group and control group depending on the treatment of chemotherapy. The experimental group were treated with Gio oxaliplatin (SOX), and patients in the control group accepted Olivier Elizabeth, leucovorin and fluorouracil (FOLFOX6) treatment. Compare and analyze the efficacy of the two groups after two cycles of therapy. Results By chemotherapy, recent efficiency and disease control rate were not significantly different (P>0.05) between the two groups;and there was also no significant difference in the incidence of adverse reactions,such as adverse reactions, fatigue weakness, gastrointestinal reactions, hand-foot syndrome, oral mucositis (P > 0.05). Conclusion The efficacy was equivalent between FOLFOX6 chemotherapy SOX test group and the control group in the treatment of elderly patients with advanced gastric , and there was no significant difference in the incidence of adverse reactions.
