Effect of plasma exchange with acupuncture point injection on liver fibrosis indexes in patients with severe hepatitis
10.3969/j.issn.1006-5725.2014.11.028
- VernacularTitle:血浆置换联合穴位注射对重型肝炎患者肝纤维化指标的影响
- Author:
Xueying QIN
;
Qifeng LU
;
Houji QIN
;
Meijin HUANG
;
Haixian QIU
;
Fenglian DENG
- Publication Type:Journal Article
- Keywords:
Hepatitis,viral,human;
Severe hepatitis;
Hepatic fibrosis;
Plasma exchange;
Acupoint injection
- From:
The Journal of Practical Medicine
2014;(11):1775-1777
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of plasma exchange with acupuncture point injection therapy on liver fibrosis indexes in patients with severe hepatitis. Methods Sixty patients with severe hepatitis were randomly divided into group A with 29 cases receiving plasma replacement and group B of 31 cases receiving astragalus injection at Zusanli point in addition to plasma replacement. Changes of liver fibrosis indexes including serum hyaluronic acid (HA), laminin (LN), collagenⅣ(Ⅳ-C), typeⅢpre-collagen (PCⅢ) were observed, which were compared with those from group C with 30 healthy subjects. Results Before treatment, there was no statistical significance in comparison of liver fibrosis index in group A and B (P>0.05), but all the indexes were higher than those in group C (P<0.001). After treatment, the level of each index in group A and B was down with a more significant change in group B and the comparison of both groups indicated statistical significance (P<0.05 or P <0.001);Compared with those in group C, changes ofⅣ-C, PCⅢin group B showed no significant difference (P>0.05). Conclusion Plasma exchange with astragalus injection at Zusanli point can effectively improve liver fibrosis indexes in patients with severe hepatitis and then improve the prognosis of patients.
