Effects of nimodipine on reducing the complications after microvascular decompression in patients with hemifacial spasm
10.3969/j.issn.1006-5725.2014.13.045
- VernacularTitle:尼莫地平减少面神经微血管减压术后面听神经相关并发症的作用
- Author:
Xu HUANG
;
Xin YAN
;
Guijun LIN
;
Feng GAO
- Publication Type:Journal Article
- Keywords:
Nimodipine;
Hemifacial spasm;
Microvascular decompression
- From:
The Journal of Practical Medicine
2014;(13):2148-2150
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate whether nimodipine could reduce complications after microvascular decompression in patients with hemifacial spasm. Methods 220 patients with hemifacial spasm , admitted into our hospital from May 2011 to Oct. 2013 , were all treated by microvascular decompression. They were divided randomly into two groups. Patients in the treatment group were treated with nimotop 50 mg/d after the operation for the first 3 days, then was orally taken 30 mg/d for a week. Patients in the control group were treated with the same after the operation without nimodipine. The postoperative complications including hearing deficit and peripheral facial paralysis were closely observed within three months after operation. Results The total effective rate was 100% in both groups. The incidence rate of peripheral facial paralysis and hearing deficit in treatment group was significant lower than that of the control group (P < 0.05). Conclusion Nimodipine has significant effect on reducing the incidence rate of peripheral facial paralysis and hearing deficit after microvascular decompression in patients with hemifacial spasm.
