The prognosis and risk stratification of patients with left main coronary artery disease after percutaneous coronary intervention or coronary artery bypass grafting
10.3969/j.issn.1006-5725.2014.11.014
- VernacularTitle:左主干病变冠脉介入或搭桥预后及危险分层的临床研究
- Author:
Chuanyan ZHAO
;
Liming CHEN
;
Lianqun CUI
- Publication Type:Journal Article
- Keywords:
Unprotected Left main coronary artery disease;
Risk stratification;
Percutaneous coronary intervention;
Coronary artery bypass grafting;
Syntax score
- From:
The Journal of Practical Medicine
2014;(11):1725-1729
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the incidence of MACE and predictors in patients with unprotected left main coronary artery disease (ULMCAD) after percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). To establish a risk stratification to guide treatment and prognosis of patients with ULMCAD who underwent PCI. Methods The incidence of MACE in 201 patients with ULMCAD who underwent PCI or CABG was compared, retrospectively. The predictors of MACE of the two groups were obtained by logistic regression analyses. The predictors of MACE of the PCI group were assigned and stratified. The validity of the risk stratification on the prediction of MACE was verified in a new group of 126 patients with ULMCAD who underwent PCI. Results The incidence of MACE of PCI and CABG group was 16% and 11.9%, respectively. Logistic regression analyses showed that LVEF, diabetes mellitus and Syntax score were related to MACE in PCI group, while age, LVEF and renal function insufficiency were related to MACE in CABG group. The verification results showed a good predictive value of the risk stratification based on LVEF, diabetes mellitus and Syntax score on the incidence of MACE. Conclusions PCI treatment in patients with ULMCAD is feasible and has a good long-term outcome. The risk stratification in accordance with LVEF, diabetes mellitus and Syntax score has good predictive value on the incidence of MACE.
