MiRNA-101 suppresses growth and invasion of human brain glioma U251 cells
- VernacularTitle:MiRNA-101抑制人脑胶质瘤细胞U251生长和侵袭
- Author:
Shuo LIU
;
Shuai LI
;
Hongyu ZHAO
;
Yunhui LIU
- Publication Type:Journal Article
- Keywords:
Glioma;
MicroRNA;
MiRNA-101;
Invasion
- From:
Journal of Chinese Physician
2014;(z1):21-23
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe effects of forced expression of miRNA -101 on glioma U251 cells proliferation and invasion. Meth ods MiRNA-101 oligoneucleotide was transfected into U 251 cells with liposome .MTT assay measured cell proliferation and Tr-answell assay detected cell invasion .Results Compared with control groups ,the growth and invasion of U251 cells transfected with miRNA-101 were decreased markably .Conclusions MiRNA-101 may play important role in inhibiting glioma cell growth and inva-sion.
