Re port of 51 cases with gastrointestinal stromal tumors
- VernacularTitle:胃肠道间质瘤51例临床分析
- Author:
Yi ZHOU
- Publication Type:Journal Article
- Keywords:
Gastrointestinal stromal tumors (GIST);
Tumor;
Prognosis;
Lymphatic metastasis;
CD117
- From:
Journal of Chinese Physician
2014;(z1):37-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical features and prognostic factors of gastrointestinal stromal tumors. Methods The clinical features and prognostic factors of51 Gastrointestinal Stromal Tumors patients ,who were treated in people`s hospital of xin-jiang ugyur antonomous region from October 1997 to October 2009, were retrospectively analyzed .Results The 1-year, 3-year, 5-year overall survival rates of 51 cases were 85.4%,76.7%,70.7%respectively, a median of 52 months.The 1-year, 3-year, 5-year overall survival rates of the patients with >4 positive lymph nodes were lower than those of patients with ≤4nodes ( P <0.05 ) , The 1-year, 3-year, 5-year overall survival rates of the patients with positive expression of CD 117 were lower than those of patients with negtive CD117( P <0.05).The 1-year, 3-year, 5-yea r overall survival rates of the patients with recurrence and metastasis were low-er than those of patients without ( P <0.05 ) .Conclusions The prognosis of gastrointestinal stromal tumors is related with the posi-tive expression of CD117, recurrence and metastasis .