Relationship between BGP with glucose and lipids metabolism in elderly men
- VernacularTitle:老年男性骨钙素与糖脂代谢的关系
- Author:
Xiaojing CHEN
;
Lu ZHOU
;
Yanhong GAO
;
Yongyu PAN
;
Yan WANG
;
Weisheng LU
;
Zhihong PAN
;
Shuyan CHEN
- Publication Type:Journal Article
- Keywords:
Osteocalcin;
Glucose;
Glycated hemoglobin;
Lipid
- From:
Journal of Chinese Physician
2014;(z1):11-13
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between serum osteocalcin and parameters of glucose and lipid metabolism in elderly men.Methods The bone metabolism index such as serum osteocalcin was measured by electrochemiluminescence immunoas -say in 206 old male patients , incluiding 69 patients with type 2 diabetes mellitus .The parameters of glucose and lipid metabolism were also measured and the correlation between the parameters and serum BGP were analyzed .Results Serum BGP and beta-CTx concen-trations were significantly lower in patients with type 2 diabetes than those in normal glucose tolerance group [ ( 9.57 ±4.74 )μg/L vs (13.22 ±10.35)μg/L, P <0.05;(0.25 ±0.19)μg/L vs (0.35 ±0.29)μg/L, P <0.05].Compared with the group in low level of BGP, fasting blood glucose and HbA1c were reduced in high-level-BGP group[(5.89 ±2.10)mmol/L vs (5.28 ±1.38)mmol/L, P<0.01;6.30%±1.03% vs 5.98%±0.61%, P <0.01].Triglyceride (TG) was positively correlated with serum BGP ( r =0.146, P =0.032).Stepwise multiple regression analysis showed that TG and HbA 1c were independently associated with serum BGP level(β=1.995, P <0.01;β=-1.483, P <0.05).Conclusions Serum TG and HbA1c are independent factors related to serum BGP in elderly men .
