Sleep Disorder and Alcohol.
10.14401/KASMED.2017.24.1.5
- Author:
Sung Bae CHO
1
;
Sang Haak LEE
Author Information
1. Department of Psychiatry, Gyeongsang National University Hospital, Jinju, Korea. lifeofzoe@gnu.ac.kr
- Publication Type:Review
- Keywords:
Alcohols;
Sleep;
Sleep apnea;
Sleep disorders
- MeSH:
Alcohols;
Apnea;
Arousal;
Central Nervous System;
Chronobiology Disorders;
Drinking;
Eating;
Humans;
Hypnotics and Sedatives;
Male;
Physiology;
Respiration;
Respiratory Center;
Respiratory Muscles;
Respiratory System;
Restless Legs Syndrome;
Sleep Apnea Syndromes;
Sleep Wake Disorders*;
Sleep, REM;
Snoring
- From:Sleep Medicine and Psychophysiology
2017;24(1):5-11
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The use of alcohol is associated with the development and worsening of sleep disorder. Alcohol is generally known to have a sedative effect, but it has an arousal or sedative effect depending on the timing and drinking dose and directly affects REM sleep physiology. Alcohol acts on the central nervous system (CNS) to interfere with the sleep-wake cycle and to affect sleep-related hormone secretion. In addition, the ingestion of alcohol pre-sleep is associated with deterioration and development of sleep related breathing disorders (SBD). The increase in resistance of the upper respiratory tract and the decrease in sensitivity of the CNS respiratory center and the respiratory muscles are major mechanisms of alcohol-induced SBD, and result in snoring or apnea in healthy men or aggravating apnea in patients with OSA. Sleep-related restless leg syndrome and circadian rhythm disorders are common in alcohol use disorder patients. This review provides an assessment of scientific studies that investigated on the impact of alcohol ingestion on nocturnal sleep physiology and sleep disorders.
