The polarization of adipose tissue macrophages and its regulatory factors
- VernacularTitle:脂肪组织巨噬细胞极化及其调控因素
- Author:
Qianqian ZHANG
;
Hong DU
- Publication Type:Journal Article
- Keywords:
Macrophage polarization;
Phenotype;
Adipose tissue;
Inflammatory reaction
- From:
Journal of Medical Postgraduates
2014;(6):643-647
- CountryChina
- Language:Chinese
-
Abstract:
Macrophages are important immunocytes in human body , playing an important role in antigen and inflammation process.In recent years , it has shown that macrophage is a kind of cell mass with high plasticity , heterogeneity , diverse and variable immune functions .They can be polarized into different phenotypes in different microenvironments or stimulations , playing different roles in the process of inflammation .There are a variety of factors which can modulate macrophage polarization process , such as the de-velopment and progression of metabolic diseases .The polarization of adipose tissue macrophages and the factors in the regulation of macrophage polarization are summarized in this paper .