The significance of the combination of serum SCC-Ag and TCT test in the screening of cervical lesions

VernacularTitle:鳞状上皮细胞癌抗原联合液基薄层细胞检测在宫颈病变筛查中的价值
Author: Hao TAN ; Guihua ZHOU
Publication Type:Journal Article
Keywords: Carcinoma,squamous cell/immunology; Carcinoma,squamous cell/blood; Cytodiagnosis/methods; Uterine cer-vical diseases/diagnosis; Mass screening
From: Journal of Chinese Physician 2014;(6):747-749
CountryChina
Language:Chinese
Abstract: Objective To explore the application of thinprep cytology test thinprep cytologic test ( TCT) and the serum squa-mous cell carcinoma antigen ( SCC-Ag) measurement in the cervical lesions screening .Methods TCT and serum SCC-Ag measure-ment were performed in 58 patients with cervical lesions .Based on pathology diagnosis , specificity and sensitivity of these two screen-ing methods were calculated .Results Sensitivity and specificity of TCT detection were 75%and 65.8%, the sensitivity and specific-ity of SCC-Ag detection was 60%and 86.9%, respectively, and specificity of combined detection were 55%and 89.4%, respective-ly.There was statistical significance in TCT test and SCC-Ag test ( P <0.05 ) , the difference had statistical significance of combined detection of both with a single TCT to detect differences ( P <0.05 ) .Conclusions The combination of TCT and SCC-Ag detection can improve specificity and there was a certain clinical application value in the screening of cervical lesions .