Mechanical embolectomy using Penumbra system for acute cerebral embolism:model establishment and finite element analysis in one case
10.3969/j.issn.2095-4344.2014.27.014
- VernacularTitle:急性脑栓塞Penumbra机械取栓：1例建模和有限元分析
- Author:
Bo LIU
;
Peng XIE
;
Zhiwei LI
- Publication Type:Journal Article
- Keywords:
intracranial embolism;
blood vessels;
finite element analysis;
mechanics
- From:
Chinese Journal of Tissue Engineering Research
2014;(27):4345-4354
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Few cases of acute cerebral embolism were treated by mechanical thrombectomy al over the world. However, there were few cases currently treated by mechanical thrombectomy using Penumbra system. It is an unclear understanding of effects on regional cerebral blood vessels using this kind of surgery.
OBJECTIVE:To describe effects of numerical simulation on regional cerebral blood vessels of an acute cerebral embolism patient by mechanical embolectomy using Penumbra system.
METHODS:A 77-year-old woman suffering from acute cerebral embolism of left middle cerebral artery was selected. Various raw data were col ected in emergency of digital subtraction angiography, then mechanical thrombectomy using Penumbra system was carried out successful y. After these raw data were processed into dimensional numerical models of two kinds of embolectomy methods (“suction bolt method from near to far”and“suction bolt method from far to near”), and then finite element analysis was carried out.
RESULTS AND CONCLUSION:Model establishment and finite element analysis were successful y conducted. Compared with“suction bolt method from near to far”,“suction bolt method from far to near”models had smal er velocity of flow in catheter and smal er wal shear stress of thrombus (P<0.01), and had larger wal shear stress of blood vessel wal , deformation of blood vessel wal (P<0.01) and deformation of thrombus (P<0.05). Results suggested that finite element analysis of mechanical embolectomy using Penumbra system can help physicians to involve in a clear understanding of their impacts on cerebral blood vessels of patients. As a research method, it is worth to continue to explore in the future.
