Curative Effect Observation of Transfer Factor Oral Solutions as Adjunctive Therapy in Elderly Patients with Recurrent Respiratory Tract Infection (RRTI)
- VernacularTitle:转移因子口服液辅助治疗反复呼吸道感染老年患者疗效观察
- Author:
Jianbo MA
- Publication Type:Journal Article
- Keywords:
Recurrent respiratory tract infection ( RRTI);
Transfer factor oral solutions;
Ederly patients;
Adjunctive therapy;
Immune function
- From:
China Pharmacist
2014;(2):260-261
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the curative effect of transfer factor oral solutions as the adjunctive therapy in ederly patients with recurrent respiratory tract infection ( RRTI) . Methods:Totally 74 ederly patients with RRTI were selected and divided into the observation group and the control group randomly. The patients in the two groups were given anti-infection and symptomatic treatment during the acute stage of attack. The patients in the observation group were additionally given transfer factor oral solutions 10ml, po, tid for 3 months. The changes in serum immunoglobulin IgG, IgA and IgM levels in the two groups before and after the medical treat-ment were compared, and the clinical curative effect and adverse drug reactions ( ADR) were observed as well. Results: After the medical treatment, the serum IgG, IgA and IgM levels in the observation group were obviously increased than before (P<0.05), while those in the control group showed no obvious changes (P>0. 05). The total clinical efficiency in the observation group was much higher than that in the control group (P<0. 01). The ADR between the two groups with light symptoms showed no statistical differ-ences (P>0. 05). Conclusion:Transfer factor oral solutions as the adjunctive therapy in ederly patients with RRTI has the favorable clinical curative effect and safety, and the underlying mechanisms may be concerned with the effect of enhancing serum immunoglobulin IgG, IgA and IgM levels, as well as humoral immune function.