Effect Comparative Analysis of Sodium Hyaluronate and Chitosan in the Prevention of Thyroid Postopera-tive Adhesion
- VernacularTitle:透明质酸钠与几丁糖预防甲状腺术后粘连效果比较分析
- Author:
Qiang SHEN
;
Quan WANG
;
Junjie YANG
- Publication Type:Journal Article
- Keywords:
Thyroid surgery;
Sodium hyaluronate;
Chitosan;
Adhesion
- From:
China Pharmacist
2014;(2):266-268
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate and compare the effect of sodium hyaluronate and chitosan in the prevention of thyroid post-operative adhesion. Methods:Totally 84 patients with thyroid operation in our hospital from August 2012 to August 2013 were select-ed, and according to the admission time, the patients were respectively divided into group A and B with 42 cases each. In order to pre-vent postoperative adhesion, group A was treated with sodium hyaluronate, and group B was treated with chitosan. The clinical curative effect of the two groups was compared. Results: The adhesion rate in group A was 14. 3%(6/42), which was higher than that in group B (3/42 7. 1%), while the difference was not statistically significant (P>0. 05). All the patients showed no bleeding, aller-gies and other adverse reactions, only in group A, 2 mild infection (4. 8%) occurred. The adverse reactions in the two groups were without significant difference (P>0.05). Conclusion: Sodium hyaluronate and chitosan both have the preventive effect on thyroid postoperative adhesion with similar efficiency and adverse reactions.
