Effect of Compound Hypoglycemic Yuye Oral Liquor Combined with Metformin and Glimepiride on of Type 2 Diabetes Mellitus
- VernacularTitle:复方降糖玉液联合二甲双胍和格列美脲治疗2型糖尿病
- Author:
Junjie LIN
;
Fang LU
;
Jianxia ZHANG
- Publication Type:Journal Article
- Keywords:
Compound hypoglycemic Yuye oral liquor;
Type 2 diabetes mellitus;
Deficiency of Qi and Yin
- From:
China Pharmacist
2014;(2):268-270
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy and safety of compound hypoglycemic Yuye oral liquor combined with metfo-ma and glimepiride in the treatment of type 2 diabetes mellitus ( deficiency of both Qi and Yin) . Methods:Totally 80 type 2 diabetes mellitus patients were randomly divided into the treatment group and the control group with 40 each, both groups were treated with met-formin hydrochloride tablets and glimepiride tablets, the treatment group was given compound hypoglycemic Yuye oral liquor additional-ly, and the treatment duration was 12 weeks. At the end of the treatment, fasting plasma glucose( FPG) , postprandial 2 hours plasma glucose(2hPG), hemoglobin A1c(HbA1c)and traditional Chinese medicine (TCM ) syndrome in the two groups were compared. Re-sults:In both groups, FPG, 2hPG and HbAlc were decreased after the treatment, and the decrease in the treatment group was more notable than that in the control group with statistically significant difference (P<0. 05 or P<0. 01). As for TCM syndrome, the score in the treatment group was lower than that in the control group with statistically significant difference (P<0. 01). The clinical efficien-cy in the treatment group was 47. 5%, that was 22. 5% in the control group, and the difference between the two groups was statistically significant (P<0. 05). Conclusion:Compound hypoglycemic Yuyeoral liquor can reduce the blood glucose in type 2 diabetes mellitus patients( deficiency of Qi and Yin) , and the improvement of clinical symptom is striking with good safety and clinical application value.
