Determination of Residual Formaldehyde Fumigation on the Surface of Pharmaceutical Equipments by AH-MT Method
- VernacularTitle:AHMT法测定制药设备表面甲醛残留
- Author:
Jie WU
;
Guanghu RUI
;
Renjie SONG
;
Wei SHENG
;
Wenjing GONG
- Publication Type:Journal Article
- Keywords:
AHMT;
Pharmaceutical equipments;
Residual formaldehyde fumigation
- From:
China Pharmacist
2014;(2):330-332
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine the residual formaldehyde fumigation on the surface of pharmaceutical equipments by AHMT method. Methods:The reaction time of AHMT was controlled in 20 min, the solution with sodium periodate was then shaken for 30 seconds and stood for 30 seconds, and then the absorbance at 550 nm was measured. Results: The linear range of formaldehyde was 0. 250~2. 495 μg·ml-1. The recovery of formaldehyde on glass plate, color steel plate and stainless steel plate was (83. 42 ± 1. 48)%(n=3), (83. 63 ± 1. 94)%(n=3)and (83. 94 ± 2. 28)%(n=3), respectively. Conclusion:The method is proved to be convenient and accurate, and is suitable for the determination of formaldehyde on the surface of pharmaceutical equipments.
